GEORGE AUGUSTUS SALA: A VISUAL APPRENTICESHIP

Cecil Augustus Joll

Nicoletta Sala

Mathematics is a branch of the science which has been used to model the natural and the biological forms, for many centuries. Pythagoras, Aristotle, Fibonacci, Cardano, Bernoulli, Euler, Laplace, Gauss, von Helmholtz, Riemann, Einstein, Thompson, Turing, Wiener, von Neumann, Keller, and others studied important applications of mathematics to life sciences and significant developments in mathema...

Augustus Desiré Waller (1856-1922).

The electrocardiograph is one of the most important instruments with which to examine the human heart and is in constant use all over the world, yet we doubt whether many physicians know who was the first man to demonstrate that the electrical response accompanying the movement of the human heart could easily be shown by a clinical application of a relatively simple instrument. In the early par...

AUGUSTUS: ab initio prediction of alternative transcripts

AUGUSTUS is a software tool for gene prediction in eukaryotes based on a Generalized Hidden Markov Model, a probabilistic model of a sequence and its gene structure. Like most existing gene finders, the first version of AUGUSTUS returned one transcript per predicted gene and ignored the phenomenon of alternative splicing. Herein, we present a WWW server for an extended version of AUGUSTUS that ...

AUGUSTUS: a web server for gene finding in eukaryotes

We present a www server for AUGUSTUS, a novel software program for ab initio gene prediction in eukaryotic genomic sequences. Our method is based on a generalized Hidden Markov Model with a new method for modeling the intron length distribution. This method allows approximation of the true intron length distribution more accurately than do existing programs. For genomic sequence data from human...